What is it?
Silkworth, 1937
“…true alcoholism is an allergic state…”
Medicine today
“…a medical condition characterized by an impaired ability to stop or control alcohol use despite adverse social, occupational, or health consequences.”
NIAAA
The Medical Record · 1937
In two short articles, the doctor put his theory in writing: alcoholism is an allergy, and willpower is not the cure.
“The inevitable conclusion is that true alcoholism is an allergic state, the result of gradually increasing sensitization by alcohol over a more or less extended period of time.”
By 1937, Dr. Silkworth had treated thousands of alcoholics at Towns Hospital and had watched Bill W. and a small band of ex-drunks stay sober. That year he put his theory before other doctors, in two papers in the Medical Record, a New York medical journal.
The first, in March, argued that true alcoholics are allergic to alcohol. Their bodies react to it in a way other people’s do not, and the craving starts only after they take a drink.
The second, in April, was about treatment. Drying a patient out was only the start. He had to understand his condition and accept it. Then he needed a real decision, not a promise to himself that would last only until the next urge to drink.
Two years later, AA’s first book would open with the same ideas, in a letter from the same doctor.
It’s 1937. Dr. Silkworth has spent years with alcoholics at Towns Hospital, and now a few of them, like Bill W., are staying sober. That spring he put his theory in a medical journal.
True alcoholism, he wrote, is an allergy. The alcoholic’s body reacts to alcohol in a way other people’s does not. The craving starts with the first drink, and only then. Even after years without a drink, the alcoholic is still allergic. One drink brings it all back.
So willpower was not the answer. A resolution to quit, he wrote, lasts only until the next urge to drink. The patient needed a decision, based on really understanding his condition. And he called that kind of decision an inspiration.
Doctors don’t call it an allergy anymore. But two years later, these ideas would open AA’s first book.
Then and now
What Silkworth told doctors in 1937, beside what the National Institute on Alcohol Abuse and Alcoholism and the Mayo Clinic say today.
The 1937 quotations are from the March paper, as reprinted by the National Library of Medicine. The right-hand column quotes or sums up the current sources listed under Sources.
Silkworth, 1937
“…true alcoholism is an allergic state…”
Medicine today
“…a medical condition characterized by an impaired ability to stop or control alcohol use despite adverse social, occupational, or health consequences.”
NIAAA
Silkworth, 1937
He compared it to hay fever: a person can go years untroubled by pollen, then grow slowly more sensitive until the attacks come.
Medicine today
“True allergies to alcohol are rare.”
Doctors use “allergy” for reactions of the immune system. Alcohol use disorder is not one.
Mayo Clinic
Silkworth, 1937
“After the first drink, and only then, does he experience the physical phenomenon of craving.”
Medicine today
Researchers describe a repeating cycle in the brain: heavy drinking, then the misery of withdrawal, then preoccupation with the next drink, each stage feeding the next.
NIAAA
Silkworth, 1937
“They are still allergic, however, and a single drink will develop the full symptomatology again.”
Medicine today
“Lasting changes in the brain caused by alcohol misuse perpetuate AUD and make individuals vulnerable to relapse.”
NIAAA
Silkworth, 1937
“He must understand and accept the situation as a law of nature operating inexorably.”
Medicine today
Behavioral treatment, three medications approved in the U.S. for alcohol use disorder, and mutual-help groups such as AA, often in combination. Genes account for about 60 percent of the risk.
NIAAA
What held up
The word “allergy” didn’t survive. The idea underneath it did: alcoholism is a medical condition, not a failure of character, and recovery starts with understanding it.
For a closer look
The idea in the second paper that sounds most like AA, why a discarded theory lives on, and where the papers are now.
In his April paper, Silkworth drew a line between two things his patients confused.
“A resolution is an expression of a momentary emotional desire to reform. Its influence lasts only until he has an impulse to take a drink.”
“A decision, on the other hand, is the expression of a mental conviction, based on an intelligent conception of his condition.” Then he went further: “We believe that this decision is in the nature of an inspiration.”
Two years later, AA’s Third Step would also begin with a decision.
In 1939 Silkworth repeated the theory in “The Doctor’s Opinion,” his letter at the front of the Big Book, and pointed back to these papers: “We believe, and so suggested a few years ago, that the action of alcohol on these chronic alcoholics is a manifestation of an allergy.”
That letter has been printed in every copy of the book since. Generations of AA members have learned to describe their drinking as an allergy, long after doctors stopped.
In 1952 two researchers, Robinson and Voegtlin, tested alcoholics for an allergic reaction to alcohol and found none. Medicine moved on to other explanations. The word stayed in AA.
The two articles are hard to find today. Reprints survive among the papers of Dr. Lawrence Kolb, a pioneer of federal addiction research, at the National Library of Medicine, which has put the text of the March paper online.
That text was made by machine reading of the old pages and has small errors in places. The quotations on this page were checked against it and against the reprints in Dale Mitchel’s 2002 biography of Silkworth, but not yet against the printed journal.